Otani is a San Francisco-based artist working in mixed media. Social issues, particularly those that affect youth, class and women are recurring themes in her work. In her painted works, paper is combined with canvas and acrylics to create texture. Three-dimensional and installation pieces are made with paper from funeral and stationery stores and objects harvested from recycle centers. Otani is on the board of National Women’s Caucus for Art and Northern California Women’s Caucus for Art. Together with partners Matthew Frederick, Stephen Wagner and Michael Yochum, Priscilla founded Arc Studios & Gallery in San Francisco in 2009.